A new study has shown that more than one in two cancer patients experienced prolonged COVID-19 symptoms for more than six months after the initial infection. According to the news agency ANI, this research has been published in the journal eLife.
The results also show that women undergoing cancer treatment are at higher risk than men. In the general population, the reported prevalence of long-term COVID-19 – also known as post-acute sequelae of SARS-CoV-2 infection (PASC) – varies from 10% to 87%, In which the symptoms persist for more than 30 days. Had severe initial COVID-19 symptoms or were hospitalized.
Lead author Anne-Marie Chaftari, Associate Professor, University of Texas MD Anderson Cancer Center, Texas, USA, said, “Although cancer patients fall into a high COVID-19 risk group, there is limited data on PASC in cancer patients and this How does it happen. affects their progress, care and treatment."
"To provide a better understanding of post-COVID-19 management among cancer patients, we sought to characterize the patterns of prolonged COVID-19 specifically in these patients," she said.
The team of scientists identified patients receiving care at the University of Texas MD Anderson Cancer Center who were diagnosed with COVID-19 between March and September 2020 and followed for 14 months through remote symptom monitoring and their usual hospital visits His progress was followed. the study.
It added that questionnaires were sent to patients daily for 14 days after initial Covid-19 diagnosis. They may experience symptoms including fatigue, cough, chest tightness, difficulty breathing, headache, fever, altered sense of smell or taste, muscle pain, gastrointestinal (GI) symptoms, sleep disturbances, and any limitation with activities of daily living. Was asked to record symptoms.
ANI reported that prolonged COVID-19 is defined as symptoms related to coronavirus that persist for more than 30 days after diagnosis or the emergence of new COVID-19 symptoms.
The team collected data for 312 cancer patients, of whom 188, or 60 percent, developed long-term COVID-19. The study noted that people who had treatment-resistant cancer at baseline, or who had a more severe acute COVID-19 infection, were less likely to develop COVID-19 in the long term.
The link between increased BP and the risk of severe acute COVID-19 is thought to be due to the binding of the COVID-19 spike protein to angiotensin-converting enzyme 2 (ACE-2), which is the target of many BP-lowering drugs. These findings may rule out that this mechanism is important for the development of Covid-19 in the long run, it was quoted by ANI.
"Our study found that long-term COVID-19 was found in the majority of our cancer patients and was more prevalent in women than men," said senior author Issam Raad, professor at the University of Texas MD Anderson Cancer Center. Were."
“Even in this high-risk patient population, longer duration of COVID-19 was not associated with higher rates of hospital admissions. We also did not find any underlying conditions or disease severity during acute COVID-19 that could predict long-term COVID-19."
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